Type 6 secretion system

The type 6 secretion system is a bacterial nanoweapon that resembles a crossbow with an arrow. Many bacteria use this machine to fire toxic arrows into competing bacteria to kill them or into host cells to manipulate them for their own advantage.

 

Bacteria use the type 6 secretion system (T6SS) to kill other bacteria with a crossbow and arrow.
Picture by Noémie Matthey.

Bacterial killer weapons as biocontrol to protect plants

To feed the growing population on our planet, we need to improve our agriculture for plants to stay healthy and produce crops efficiently. One way to protect plants from diseases is to use biocontrol bacteria that actively kill intruding pathogens. Hence, by increasing our food supply, bacteria can help us save this planet.

Bacteria have many different type 6 secretion system crossbows that they can choose from in specific times.

Nanoweapons make the killer differences in bacterial siblings

Bacteria can be harmless or dangerous to us and other organisms in the environment. But how does a bacterium become a fighter ready to kill others? It comes all down to their toxic bullets. Here we will look at how bacterial siblings use different weapons to fight off not only their enemies but also each other.

Bacteria use the type 6 secretion system (T6SS) to kill other bacteria with a crossbow and arrow.

Bacteria fire powerful and lethal arrows to kill their competitors

When bacteria fight competitors with their type 6 secretion system nanoweapons, they shoot deadly arrows. These arrows are made of specific parts that interact with each other in unique ways for each arrow. Here, we will look at these different parts: the tip, the spike and the toxin.

Vibrio bacteria use their T6SS killing machine for movement or DNA uptake.

Should I kill or should I go? Bacteria making decisions

Bacteria have powerful killing machines with which they carve out their own niches. To kill competitors, bacteria from the Vibrio family, have a powerful crossbow and its arrows availble. However, these bacteria can decide whether they risk a kill and take up what’s left of the dead prey or they escape the dangerous situation. Here, we look at how bacteria decide to kill or flee.

Bacteria use the type 6 secretion system (T6SS) to kill other bacteria with a crossbow and arrow.

A bacterial nanoweapon called the type 6 secretion system

Bacterial killing is happening everywhere where bacteria fight for space and nutrients. Some bacteria have highly efficient weapons to kill other microbes. These killer bacteria can survive in the rarest and driest environmental niches. Just by killing other bacteria.
What kind of fantastic nanoweapon is that?